A New Chromosome Abnormality in Chronic Granulocytic Leukaemia

Leukapheresis for papilloedema in chronic granulocytic leukaemia.

Bone lesions in chronic granulocytic leukaemia.

Radiographic abnormalities in bone are unusual during the stable phase of chronic granulocytic leukaemia (CGL). A rare situation is reported in which a patient developed three distinctive skeletal lesions simultaneously in different anatomical sites. Firstly, in both fibulae symmetrical punched out and permeative lesions were present throughout much of the shafts, being most prominent in the mi...

A complex pattern of chromosome abnormalities in the acute phase of chronic granulocytic leukaemia.

The Philadelphia chromosome (Ph') is of particular interest because of its close association with chronic granulocytic leukaemia. Ph' is a distinct chromosome abnormality which is found in the marrow or blood cells of nearly all patients with this leukaemia, and appears to be generally specific to this or closely related disorders. Because of these features, Ph', unlike the chromosome abnormali...

Chronic granulocytic leukaemia developing upon a follicular lymphoma.

Leukaemia has been reported' recently in association with apparently unrelated haematological malignancies in patients treated with cytotoxic drugs. These leukaemias are mainly acute myeloid or variants such as acute myelomonocytic3 or erythroleukaemia.' We describe a case of chronic granulocytic leukaemia (CGL) developing in a patient with a non-Hodgkin's lymphoma treated with alkylating agent...

Megakaryoblastic transformation of chronic granulocytic leukaemia: a case report.

The patient is a 38 year old Malay woman who was first seen in General Hospital, Kuala Lumpur in February 1980. She presented then with a few months history of progressive abdominal discomfort, low grade fever and lethargy. On examination she was pale and had hepatomegaly of 3 cm and splenomegaly of 20 cm. Her full blood picture showed haemoglobin of 6.8 gldl, total white cell count of 313.5 x ...